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2021 GMC Sierra 2500HD for sale

All available 2021 GMC Sierra 2500HD listings.

1,373 listings • $25,485 – $114,999 • avg 67,782 mi

Featured listings

Browse all 1,373 2021 gmc sierra 2500hd for sale →
2021 GMC Sierra 2500HD AT4 — Pickup Truck — 145,784 mi — Seymour, IN Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

AT4 · 4WD · Automatic

145,784 miGas Summit White

$40,990

Seymour, IN

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2021 GMC Sierra 2500HD Base — Pickup Truck — 137,099 mi — Abilene, TX Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

Base · 4WD · Automatic

137,099 miDiesel Summit White

$37,304

Abilene, TX

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2021 GMC Sierra 2500HD AT4 — Pickup Truck — 59,391 mi — Mesquite, TX Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

AT4 · 4WD · Automatic

59,391 miGas Summit White

$52,799

Mesquite, TX

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2021 GMC Sierra 2500HD AT4 — Pickup Truck — 59,606 mi — Coon Rapids, MN Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

AT4 · 4WD · Automatic

59,606 miGas Onyx Black

$51,499

Coon Rapids, MN

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2021 GMC Sierra 2500HD AT4 — Pickup Truck — 55,664 mi — Concord, CA Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

AT4 · 4WD · Automatic

55,664 miDiesel Summit White

$63,995

Concord, CA

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2021 GMC Sierra 2500HD Denali — Pickup Truck — 95,206 mi — Jacksonville, NC Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

Denali · 4WD · Automatic

95,206 miDiesel Pacific Blue Metallic

$57,900

Jacksonville, NC

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2021 GMC Sierra 2500HD Base — Pickup Truck — 49,848 mi — Raleigh, NC Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

Base · RWD · Automatic

49,848 miGas Summit White

$41,246

Raleigh, NC

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2021 GMC Sierra 2500HD SLE — Pickup Truck — 90,949 mi — Anchorage, AK Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

SLE · 4WD · Automatic

90,949 miGas Blue

$43,995

Anchorage, AK

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2021 GMC Sierra 2500HD SLE — Pickup Truck — 105,981 mi — Blackfoot, ID Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

SLE · 4WD · Automatic

105,981 miGas White

$44,753

Blackfoot, ID

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2021 GMC Sierra 2500HD AT4 — Pickup Truck — 68,160 mi — Raleigh, NC Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

AT4 · 4WD · Automatic

68,160 miDiesel Onyx Black

$58,150

Raleigh, NC

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2021 GMC Sierra 2500HD Denali — Pickup Truck — 68,977 mi — Grand Junction, CO Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

Denali · 4WD · Automatic

68,977 miDiesel Onyx Black

$59,995

Grand Junction, CO

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2021 GMC Sierra 2500HD Denali — Pickup Truck — 50,528 mi — Colorado Springs, CO Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

Denali · 4WD · Automatic

50,528 miDiesel Summit White

$62,521

Colorado Springs, CO

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2021 GMC Sierra 2500HD AT4 — Pickup Truck — 50,670 mi — Reno, NV Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

AT4 · 4WD · Automatic

50,670 miDiesel Summit White

$69,984

Reno, NV

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2021 GMC Sierra 2500HD AT4 — Pickup Truck — 39,257 mi — Concord, NH Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

AT4 · 4WD · Automatic

39,257 miDiesel Ebony Twilight Metallic

$63,987

Concord, NH

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2021 GMC Sierra 2500HD Denali — Pickup Truck — 44,734 mi — Glendale, AZ Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

Denali · 4WD · Automatic

44,734 miDiesel Ebony Twilight Metallic

$63,985

Glendale, AZ

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2021 GMC Sierra 2500HD AT4 — Pickup Truck — 53,112 mi — National City, CA
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

AT4 · 4WD · Automatic

53,112 miDiesel Summit White

$62,995

National City, CA

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2021 GMC Sierra 2500HD AT4 — Pickup Truck — 45,463 mi — Fall River, MA Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

AT4 · 4WD · Automatic

45,463 miGas Pacific Blue Metallic

$52,630

Fall River, MA

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2021 GMC Sierra 2500HD AT4 — Pickup Truck — 66,754 mi — Winter Haven, FL Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

AT4 · 4WD · Automatic

66,754 miDiesel Summit White

Contact for price

Winter Haven, FL

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2021 GMC Sierra 2500HD Denali — Pickup Truck — 64,531 mi — Darlington, SC Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

Denali · 4WD · Automatic

64,531 miDiesel White Frost Tricoat

$63,878

Darlington, SC

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2021 GMC Sierra 2500HD Denali — Pickup Truck — 86,306 mi — Plainfield, IN Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

Denali · 4WD · Automatic

86,306 miDiesel Quicksilver Metallic

$55,000

Plainfield, IN

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2021 GMC Sierra 2500HD Denali — Pickup Truck — 25,166 mi — Matthews, NC Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

Denali · 4WD · Automatic

25,166 miDiesel Summit White

$65,577

Matthews, NC

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2021 GMC Sierra 2500HD SLT — Pickup Truck — 84,371 mi — Fargo, ND Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

SLT · 4WD · Automatic

84,371 miGas Summit White

$47,240

Fargo, ND

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2021 GMC Sierra 2500HD AT4 — Pickup Truck — 61,084 mi — Jacksonville, NC Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

AT4 · 4WD · Automatic

61,084 miDiesel Summit White

$61,315

Jacksonville, NC

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2021 GMC Sierra 2500HD Denali — Pickup Truck — 71,393 mi — Elyria, OH Clean title
GMC logo

USED · Pickup Truck

2021 GMC Sierra 2500HD

Denali · 4WD · Automatic

71,393 miGas Summit White

$55,222

Elyria, OH

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About this category

The 2021 GMC Sierra 2500HD is currently available in 1,373 listings on Carlify. Average mileage across these listings is 67,782 miles. Pricing starts at $25,485 and reaches $114,999. Browse photos, full vehicle history, and dealer details for each 2021 Sierra 2500HD.

Frequently asked questions

How much does a 2021 GMC Sierra 2500HD cost used?
2021 GMC Sierra 2500HD listings range from $25,485 to $114,999, averaging $56,787 on Carlify.
How many 2021 GMC Sierra 2500HD are listed?
Carlify shows 1,373 active 2021 GMC Sierra 2500HD listings.
What's the average mileage on a 2021 GMC Sierra 2500HD?
Average mileage across 2021 GMC Sierra 2500HD listings is 67,782 miles.

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